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Asymmetric Permanganate‐Promoted Oxidative Cyclization of 1,5‐Dienes by Using Chiral Phase‐Transfer Catalysis
Author(s) -
Brown Richard C. D.,
Keily John F.
Publication year - 2001
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20011203)40:23<4496::aid-anie4496>3.0.co;2-f
Subject(s) - catalysis , phase (matter) , oxidative phosphorylation , potassium permanganate , chemistry , permanganate , work (physics) , medicinal chemistry , stereochemistry , organic chemistry , engineering , biochemistry , mechanical engineering
Up to four new stereocenters are created with control of the relative and absolute stereochemistry in a single step in the unusual phase‐transfer‐catalyzed oxidative cyclization of achiral dienes with permanganate (see scheme).