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Unichemo Protection: A Concept for Chemical Synthesis
Author(s) -
Miranda Les P.,
Meldal Morten
Publication year - 2001
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20011001)40:19<3655::aid-anie3655>3.0.co;2-k
Subject(s) - protecting group , derivatization , combinatorial chemistry , functional group , chemical synthesis , chemistry , organic chemistry , polymer , biochemistry , alkyl , high performance liquid chromatography , in vitro
Modular cleavage of oligomer protecting groups is at the heart of the unichemo‐protection (UCP) strategy (see scheme) that simplifies synthesis and facilitates construction of polyfunctional molecules.