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Decoding Products of Diversity Pathways from Stock Solutions Derived from Single Polymeric Macrobeads
Author(s) -
Blackwell Helen E.,
Pérez Lucy,
Schreiber Stuart L.
Publication year - 2001
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20010917)40:18<3421::aid-anie3421>3.0.co;2-b
Subject(s) - decoding methods , stock (firearms) , binary number , computer science , information retrieval , arithmetic , algorithm , mathematics , engineering , mechanical engineering
Binary encoding with chloroaromatic diazoketone tags allows for efficient decoding from either beads ( 1 ) or stock solutions ( 2 ), which were derived from a “one‐bead, one‐stock‐solution” chemical technology platform. This process is demonstrated in the partial decoding of a library of 4,320 dihydropyrancarboxamides.