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Medicinal Chemistry: Challenges and Opportunities
Author(s) -
Wess Günther,
Urmann Matthias,
Sickenberger Birgitt
Publication year - 2001
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20010917)40:18<3341::aid-anie3341>3.0.co;2-d
Subject(s) - bottleneck , computational biology , human genome , genome , drug discovery , chemistry , computer science , biology , bioinformatics , biochemistry , gene , embedded system
The sequencing of the human genome has led to a wealth of new pharmaceutical targets. However, medicinal chemistry has proved to be a bottleneck in the search for active drugs. This bottleneck can be overcome by chemical biology, which is crucial in the transition from a trial‐and‐error mentality to a predictive approach.