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Rational Design of Low Molecular Mass Organogelators: Toward a Library of Functional N ‐Acyl‐1, ω ‐Amino Acid Derivatives
Author(s) -
MiedenGundert Gudrun,
Klein Lars,
Fischer Marco,
Vögtle Fritz,
Heuzé Karine,
Pozzo JeanLuc,
Vallier Martine,
Fages Frédéric
Publication year - 2001
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20010903)40:17<3164::aid-anie3164>3.0.co;2-b
Subject(s) - chemistry , amino acid , alkali metal , rational design , acylation , organic chemistry , combinatorial chemistry , biochemistry , catalysis , nanotechnology , materials science
N ‐Acyl amino acids RCONH(CH 2 ) n COOR 1 represent a new family of organogelators that can be obtained in a combinatorial approach from libraries of activated acids and amino acids. The amounts required for gel formation (see picture) in solvents such as DMF are less than 1 mg mL −1 and the gels formed are very stable. n =5, 7, 10, 12; R=aromatic or aliphatic group; R 1 =H or alkali metal (Na).