Premium
Methylenation of Aldehydes: Transition Metal Catalyzed Formation of Salt‐Free Phosphorus Ylides
Author(s) -
Lebel Hélène,
Paquet Valérie,
Proulx Caroline
Publication year - 2001
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20010803)40:15<2887::aid-anie2887>3.0.co;2-q
Subject(s) - salt (chemistry) , catalysis , transition metal , phosphorus , chemistry , inorganic chemistry , metal , organic chemistry
A variety of terminal alkenes are produced in excellent yields by the rhodium( I )‐catalyzed methylenation of aldehydes using TMSCHN 2 and PPh 3 [Eq. (1)]. These mild reaction conditions allowed the conversion of enolizable substrates and the chemoselective methylenation of aldehydes over ketones. TMS=trimethylsilyl.