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Catalytic Use of a Boron Source for Boron Enolate Mediated Stereoselective Aldol Reactions in Water
Author(s) -
Mori Yuichiro,
Manabe Kei,
Kobayashi Shū
Publication year - 2001
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20010803)40:15<2815::aid-anie2815>3.0.co;2-f
Subject(s) - aldol reaction , boron , stereoselectivity , catalysis , chemistry , aldol condensation , organic chemistry
Use of boron enolates in water! Boron enolates can be generated and used for aldol reactions in water by using a catalytic amount of Ph 2 BOH (see scheme). This is the first example of a catalytic use of a boron source in stereoselective aldol reactions mediated by boron enolates. The mechanism of the reaction is discussed.