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Gold Glyconanoparticles as Water‐Soluble Polyvalent Models To Study Carbohydrate Interactions
Author(s) -
de la Fuente Jesús M.,
Barrientos Africa G.,
Rojas Teresa C.,
Rojo Javier,
Cañada Javier,
Fernández Asunción,
Penadés Soledad
Publication year - 2001
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20010618)40:12<2257::aid-anie2257>3.0.co;2-s
Subject(s) - carbohydrate , water soluble , chemistry , nanotechnology , materials science , organic chemistry
Glycosphingolipid clustering and interactions at the cell membrane can be modeled by gold glyconanoparticles prepared with biologically significant oligosaccharides. Such water‐soluble gold glyconanoparticles with highly polyvalent carbohydrate displays (see picture, gray hemisphere: gold nanoparticle) have been obtained by a simple and versatile strategy.