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An Atom‐Economic Three‐Carbon Chain Extension to Give Enamides
Author(s) -
Trost Barry M.,
Surivet JeanPhilippe
Publication year - 2001
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20010417)40:8<1468::aid-anie1468>3.0.co;2-f
Subject(s) - extension (predicate logic) , carbon atom , carbon chain , atom (system on chip) , chain (unit) , ruthenium , chemistry , carbon fibers , trimethylsilyl , catalysis , stereochemistry , combinatorial chemistry , medicinal chemistry , organic chemistry , mathematics , computer science , physics , parallel computing , programming language , alkyl , astronomy , composite number , algorithm
Di‐ or trisubstituted alkenes of defined geometry , with terminal enamide groups, are formed in an atom‐economic three‐carbon chain extension of alkynes with allyl amides catalyzed by ruthenium (see, for example, Equation (1); Boc= tert ‐butoxycarbonyl, TMS=trimethylsilyl).