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Highly Efficient and Ultrafast Phototriggers for cAMP and cGMP by Using Long‐Wavelength UV/Vis‐Activation
Author(s) -
Hagen Volker,
Bendig Jürgen,
Frings Stephan,
Eckardt Torsten,
Helm Siegrun,
Reuter Dirk,
Kaupp U. Benjamin
Publication year - 2001
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20010316)40:6<1045::aid-anie10450>3.0.co;2-f
Subject(s) - ultrashort pulse , wavelength , biophysics , optoelectronics , chemistry , materials science , physics , optics , biology , laser
Caged cyclic nucleotides exhibiting remarkable advantageous properties have been developed through the use of novel photolabile coumarinylmethyl protecting groups (see scheme). They serve as excellent intracellular sources of cAMP and cGMP and allow the study of spatial‐ and time‐dependent aspects of cyclic nucleotide signaling.