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Recent Developments in Catalytic Asymmetric Strecker‐Type Reactions
Author(s) -
Yet Larry
Publication year - 2001
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20010302)40:5<875::aid-anie875>3.0.co;2-c
Subject(s) - strecker amino acid synthesis , enantiopure drug , enantioselective synthesis , chemistry , catalysis , cyanide , component (thermodynamics) , organic chemistry , physics , thermodynamics
150 years after its discovery , a truly efficient three‐component asymmetric version of the Strecker reaction has finally been accomplished; there has also been significant progress in recent years in two‐component Strecker‐type systems: Enantiopure amino acids can now be obtained from enantioselective catalysis of the Strecker reaction with different cyanide sources and aldimines (see scheme).