Premium
Narrow Molecular Weight Distribution Precursors for Polymer–Drug Conjugates
Author(s) -
Godwin Antony,
Hartenstein Markus,
Müller Axel H. E.,
Brocchini Stephen
Publication year - 2001
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20010202)40:3<594::aid-anie594>3.0.co;2-p
Subject(s) - polymer , chemistry , conjugate , distribution (mathematics) , drug , molar mass distribution , combinatorial chemistry , organic chemistry , biology , pharmacology , mathematical analysis , mathematics
Atom transfer polymerization has been used to prepare a narrow molecular weight distribution (MWD), active ester homopolymer that acted as a precursor to prepare families of narrow MWD polymer–drug conjugates during preclinical studies (see schematic representation).