Premium
Stereoselective Multiple Functionalization of Pyrylium Salts by Domino Reactions with 2‐Silyloxybuta‐1,3‐dienes
Author(s) -
Beifuss Uwe,
Goldenstein Kim,
Döring Frank,
Lehmann Christopher,
Noltemeyer Mathias
Publication year - 2001
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20010202)40:3<568::aid-anie568>3.0.co;2-l
Subject(s) - surface modification , stereoselectivity , domino , chemistry , combinatorial chemistry , organic chemistry , catalysis
Six at a time! Up to six stereogenic centers can be diastereoselectively formed in one step in three‐component domino reactions of 4‐silyloxypyrylium triflates with 2‐silyloxybuta‐1,3‐dienes. Annulated or bridged ring systems such as 1 and 2 , respectively, can be formed with high selectivity. R 1 =silyl group; R 2 , R 3 =organyl group.