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Stereochemical Assignment of the C21–C38 Portion of the Desertomycin/Oasomycin Class of Natural Products by Using Universal NMR Databases: Proof
Author(s) -
Tan ChoonHong,
Kobayashi Yoshihisa,
Kishi Yoshito
Publication year - 2000
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20001201)39:23<4282::aid-anie4282>3.0.co;2-u
Subject(s) - diastereomer , stereoselectivity , natural product , chemical shift , natural (archaeology) , stereochemistry , chemistry , class (philosophy) , organic chemistry , computer science , catalysis , geography , archaeology , artificial intelligence
Stereochemistry can be predicted : The stereoselective synthesis of the C21–C38 degradation product derived from oasomycins A and B (see picture) has confirmed the stereochemistry predicted from a comparitive study of the NMR chemical shifts of the C21–C38 portion of the natural products with those obtained for its diastereomers.