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A New Highly Efficient Catalyst System for the Coupling of Nonactivated and Deactivated Aryl Chlorides with Arylboronic Acids
Author(s) -
Zapf Alexander,
Ehrentraut Andreas,
Beller Matthias
Publication year - 2000
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20001117)39:22<4153::aid-anie4153>3.0.co;2-t
Subject(s) - aryl , catalysis , steric effects , chemistry , combinatorial chemistry , palladium , organic chemistry , alkyl
A new record in chloroarene activation: Even electron‐rich and sterically hindered chloroarenes can now be coupled by using the phosphane diadamantyl‐ n ‐butylphosphane (BuPAd 2 ) in palladium‐catalyzed reactions with aryl boronic acids [Eq. (1)]. The catalyst system is the most productive and most active currently known for the Suzuki reaction of chloroarenes.