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A New Efficient Synthesis of ( R , R )‐2,2′‐Bipyrrolidine: An Interesting Chiral 1,2‐Diamine with C 2 Symmetry
Author(s) -
Alexakis Alexandre,
Tomassini Axel,
Chouillet Cyril,
Roland Sylvain,
Mangeney Pierre,
Bernardinelli Gerald
Publication year - 2000
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20001117)39:22<4093::aid-anie4093>3.0.co;2-r
Subject(s) - diamine , symmetry (geometry) , molecule , stereochemistry , chemistry , mathematics , polymer chemistry , geometry , organic chemistry
Making stairs: A new conformational concept is presented for the synthesis of derivatives of C 2 ‐symmetrical 1,2‐diamines, where a stairlike arrangement is imposed on the molecule. A new efficient synthesis of ( R , R )‐bipyrrolidine is described; the picture shows the X‐ray structure of the ( R , R )‐bipyrrolidine/ZnCl 2 complex.