Premium
Enzymatic Glycosylation in Plasticized Glass Phases: A Novel and Efficient Route to O‐Glycosides
Author(s) -
Gill Iqbal,
Valivety Rao
Publication year - 2000
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20001103)39:21<3804::aid-anie3804>3.0.co;2-1
Subject(s) - glycoside , monosaccharide , glycosylation , chemistry , molecule , enzyme , organic chemistry , glycoside hydrolase , combinatorial chemistry , stereochemistry , biochemistry
Glycosidases are active in plasticized glasses formed from mixtures of monosaccharides, alkylglycosides, and a variety of hydroxylated molecules. This enables a novel and efficient approach to the synthesis of a range of glycosides with yields of 39–71 % and unprecedented productivities of 0.13–0.65 grams per gram of reaction mixture (see scheme).