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Fast, Convenient, and Efficient Molybdenum‐Catalyzed Asymmetric Allylic Alkylation under Noninert Conditions: An Example of Microwave‐Promoted Fast Chemistry
Author(s) -
Kaiser NilsFredrik K.,
Bremberg Ulf,
Larhed Mats,
Moberg Christina,
Hallberg Anders
Publication year - 2000
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20001016)39:20<3595::aid-anie3595>3.0.co;2-s
Subject(s) - tsuji–trost reaction , molybdenum , enantioselective synthesis , alkylation , catalysis , allylic rearrangement , microwave , chemistry , molybdenum oxide , ligand (biochemistry) , combinatorial chemistry , organic chemistry , computer science , biochemistry , receptor , telecommunications
Microwave heating allows regio‐ and enantioselective allylic alkylation to be carried out in air in a few minutes in a convenient one‐pot procedure [Eq. (1)]. The catalytically active molybdenum( 0 ) species was formed in situ from inexpensive [Mo(CO) 6 ] and a chiral ligand.