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Tecto‐RNA: One‐Dimensional Self‐Assembly through Tertiary Interactions
Author(s) -
Jaeger Luc,
Leontis Neocles B.
Publication year - 2000
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20000717)39:14<2521::aid-anie2521>3.0.co;2-p
Subject(s) - modularity (biology) , rna , modular design , biology , oligomer , computational biology , computer science , chemistry , genetics , gene , programming language , organic chemistry
The modularity of natural RNA is the basis for the design of tecto‐RNA, modular RNA units capable of directed self‐assembly. One such modular association through specific RNA loop–receptor tertiary interactions, which leads to one‐dimensional oligomer arrays, is demonstrated (see picture).