Premium
Bicyclo[3.2.1]DNA: On the Structural and Energetic Role of the Furanose Subunit in Complementary Strand Recognition of DNA
Author(s) -
Keller Bernhard M.,
Leumann Christian J.
Publication year - 2000
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20000703)39:13<2278::aid-anie2278>3.0.co;2-#
Subject(s) - furanose , dna , protein subunit , stereochemistry , bicyclic molecule , biology , genetics , computational biology , microbiology and biotechnology , chemistry , ring (chemistry) , gene , organic chemistry
Despite a flexible linking unit between the base and backbone , bicyclo[3.2.1]DNA preserves a DNA‐like base‐pairing behavior system, such as selective Watson–Crick base‐pair formation (see picture) with an antiparallel alignment of strands in the duplex.