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β ‐Catenin, Cyclins, and More: New Insights into the Pathogenesis, Treatment, and Prevention of Colon Cancer
Author(s) -
Giannis Athanassios
Publication year - 2000
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20000703)39:13<2261::aid-anie2261>3.0.co;2-6
Subject(s) - pathogenesis , colorectal cancer , catenin , cancer research , disease , cancer , medicine , bioinformatics , biology , computational biology , wnt signaling pathway , immunology , genetics , signal transduction
Colon cancer is widespread in western populations. In many cases, the proteins β ‐catenin and APC play a decisive role. New research results give an insight into the molecular connections which eventually cause the disease, and suggest new ways not only for prevention but also for the improvement of existing drugs and the development of new therapies.