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Guest Penetration Deep within the Cavity of Calix[4]arene Hosts: The Tight Binding of Nitric Oxide to Distal (Cofacial) Aromatic Groups
Author(s) -
Rathore Rajendra,
Lindeman Sergey V.,
Rao Kolluri S. S. P.,
Sun Duoli,
Kochi Jay K.
Publication year - 2000
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20000616)39:12<2123::aid-anie2123>3.0.co;2-4
Subject(s) - nitric oxide , conformational isomerism , chemistry , ether , oxide , crystallography , calixarene , stereochemistry , photochemistry , molecule , organic chemistry
Nitric oxide in solitary confinement : Conformationally mobile p‐tert ‐butylcalix[4]arene methyl ether captures nitric oxide (NO) with unprecedented efficiency ( K >5×10 8 M −1 ) upon oxidative activation. X‐ray crystallographic and NMR spectroscopic studies confirm that NO penetrates deep into the interior of the quasi‐cylindrical cavity of the 1,3‐alternate conformer (see picture).