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Synthetic Applications of Electrophilic Fluorodesilylation
Author(s) -
Gouverneur Véronique,
Greedy Benjamin
Publication year - 2002
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/1521-3765(20020215)8:4<766::aid-chem766>3.0.co;2-u
Subject(s) - electrophile , fluorine , reagent , electrophilic fluorination , chemistry , combinatorial chemistry , organic chemistry , molecule , catalysis
Recently, with the appearance of electrophilic sources of fluorine including the commercially available N−F reagents, the concept of electrophilic fluorodesilylation has emerged as a new strategy to prepare a variety of fluorine containing compounds. This paper highlights how this concept has been applied to the preparation of a series of fluorinated molecules including fluoroaromatic compounds, fluoroalkenes, difluoroamides, difluoroalcohols, difluoroethers and α ‐fluorinated carbonyl derivatives.