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Bioorganic Applications of Semisynthetic DNA–Protein Conjugates
Author(s) -
Niemeyer Christof M.
Publication year - 2001
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/1521-3765(20010803)7:15<3188::aid-chem3188>3.0.co;2-c
Subject(s) - biochip , conjugate , nanotechnology , supramolecular chemistry , combinatorial chemistry , dna , chemistry , materials science , molecule , computational biology , biochemistry , biology , organic chemistry , mathematical analysis , mathematics
Semisynthetic DNA–protein conjugates are versatile molecular tools useful, for instance, in the self‐assembly of high‐affinity reagents for immunological detection assays, the fabrication of highly functionalized laterally microstructured biochips, and the biomimetic “bottom‐up” synthesis of nanostructured supramolecular devices. This concept paper summarizes the current state‐of‐the‐art concerning the synthesis, characterization, and applications of such hybrid molecules, and also draws perspectives on future developments.