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Molecular Recognition of Carbohydrates by Artificial Receptors: Systematic Studies towards Recognition Motifs for Carbohydrates
Author(s) -
Mazik Monika,
Sicking Willi
Publication year - 2001
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/1521-3765(20010202)7:3<664::aid-chem664>3.0.co;2-e
Subject(s) - molecular recognition , hydrogen bond , amide , chemistry , receptor , covalent bond , molecule , combinatorial chemistry , biochemistry , stereochemistry , organic chemistry
The synthesis and binding properties for carbohydrates of several artificial, acyclic receptors containing two or three heterocyclic recognition units covalently attached to a phenyl spacer is described. These host molecules having uncharged hydrogen‐bonding sites were used in a systematic study towards the evaluation of recognition motifs for carbohydrates. A novel effective, acyclic hydrogen‐bonding receptor possessing naphthyridine–amide moieties as heterocyclic recognition units has been developed.