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Retinal stem cells in vertebrates
Author(s) -
Perron Muriel,
Harris William A.
Publication year - 2000
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/1521-1878(200008)22:8<685::aid-bies1>3.0.co;2-c
Subject(s) - retina , biology , retinal , stem cell , fish <actinopterygii> , anatomy , microbiology and biotechnology , zoology , neuroscience , fishery , botany
In fish and amphibia, retinal stem cells located in the periphery of the retina, the ciliary marginal zone (CMZ), produce new neurons in the retina throughout life. In these species, the retina grows to keep pace with the enlarging body. When birds or mammals reach adult proportions, however, their retinas stop growing so there appears to be no need for such a proliferative area with stem cells. It is a surprise, therefore, that recent data suggest that a region similar to the CMZ of fish and amphibia exists in the postnatal chick and the adult mouse.(1–3) BioEssays 22:685–688, 2000. © 2000 John Wiley & Sons, Inc.