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Excited‐State Photophysics of an Acridine Derivative Selectively Intercalated in Duplex DNA
Author(s) -
Hess Stephan,
Davis William B.,
Voityuk Alexander A.,
Rösch Notker,
MichelBeyerle Maria E.,
Ernsting Nikolaus P.,
Kovalenko Sergeij A.,
Pérez Lustres J. Luis
Publication year - 2002
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/1439-7641(20020517)3:5<452::aid-cphc452>3.0.co;2-k
Subject(s) - acridine , chemistry , duplex (building) , excited state , dna , derivative (finance) , photochemistry , aggregation induced emission , fluorescence , organic chemistry , biochemistry , physics , financial economics , economics , quantum mechanics , nuclear physics
Faster than 200 fs is the time scale of dynamic solvation of an acridine derivative (ACMA) intercalated into an abasic site of the DNA duplex. This observation implies that the Stokes shift of 0.41 eV is due to ultrafast repolarization of the nuclear degrees of freedom of the DNA pocket. In this system, the environmental reorganization induced by the dipole moment change of 3–4 Debye upon excitation may involve both π–π interactions between ACMA and the adjacent nucleobases as well as polar interactions exerted by the hydrogen bonds of these base pairs.