Premium
The Desorption Process of Macromolecules Adsorbed on Interfaces: The Force Spectroscopy Approach
Author(s) -
Conti Matteo,
Bustanji Yasser,
Falini Giuseppe,
Ferruti Paolo,
Stefoni Sergio,
Samorì Bruno
Publication year - 2001
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/1439-7641(20011015)2:10<610::aid-cphc610>3.0.co;2-6
Subject(s) - macromolecule , force spectroscopy , polymer , desorption , adsorption , chemical physics , surface forces apparatus , chemistry , surface (topology) , spectroscopy , materials science , atomic force microscopy , nanotechnology , chemical engineering , organic chemistry , physics , biochemistry , geometry , mathematics , quantum mechanics , engineering
They're flexible and sticky : While investigations of the very stiff DNA molecular conformation on surfaces have been made, the equivalent for more typical macromolecules is complicated by their shorter persistance length. A gentle detachment study with a polymer bound to an SFM tip allows the forces between the polymer and surface to be probed; the detachement force required depends on the surface conformation, whether only a small loop or a long tail must be peeled from the surface, as shown by the cartoon.