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Towards Proto‐Cells: “Primitive” Lipid Vesicles Encapsulating Giant DNA and Its Histone Complex
Author(s) -
Nomura Shinichirou M.,
Yoshikawa Yuko,
Yoshikawa Kenichi,
Dannenmuller Olivier,
ChasserotGolaz Sylvette,
Ourisson Guy,
Nakatani Yoichi
Publication year - 2001
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/1439-7633(20010601)2:6<457::aid-cbic457>3.0.co;2-f
Subject(s) - vesicle , nucleic acid , dna , fluorescence , chemistry , biophysics , histone , lipid vesicle , molecule , biochemistry , microbiology and biotechnology , biology , membrane , organic chemistry , physics , quantum mechanics
An important prebiotic event was probably the incorporation of nucleic acids by lipid vesicles. This process was studied with artificial model cells and fluorescent probes. Pictures 1–4 represent a time series of fluorescence microscopic images of T4 DNA molecules (166 kb) incorporated into giant vesicles of 5 μm diameter. The entrapped DNA molecules are in a coiled state.