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Lipase‐catalyzed synthesis of quinate and glucuronate fatty esters
Author(s) -
Villeneuve Pierre,
Hills Geoffrey,
Bachain Phillipe,
Pina Michel,
Caro Yanis,
Baréa Bruno,
Guyot Bernard,
Grüning Burghard,
Graille Jean
Publication year - 2002
Publication title -
european journal of lipid science and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.614
H-Index - 94
eISSN - 1438-9312
pISSN - 1438-7697
DOI - 10.1002/1438-9312(200207)104:7<394::aid-ejlt394>3.0.co;2-k
Subject(s) - chemistry , lipase , catalysis , glucuronate , organic chemistry , fatty acid , butanol , glucuronic acid , alkyl , substrate (aquarium) , alcohol , quinic acid , glucuronates , solvent , ethanol , biochemistry , enzyme , polysaccharide , oceanography , geology
The lipase‐catalyzed synthesis of fatty alcohol esters of quinic and glucuronic acid was investigated. The results showed that although a direct esterification process was possible, a strategy involving short‐chain alkyl ester intermediates was advantageous. 2‐Methyl‐2‐butanol was chosen as solvent and parameters such as substrate ratios and concentrations were optimized. Octyl, decyl and hexadecyl esters of quinic and glucuronic acids could be obtained with this process. However, reaction rates were rather slow and it could be shown that the completely chemically catalyzed synthesis of the same products using ion exchange resins was advantageous.