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Limits to potent antiretroviral therapy
Author(s) -
Telenti Amalio,
Paolo Rizzardi G.
Publication year - 2000
Publication title -
reviews in medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.06
H-Index - 90
eISSN - 1099-1654
pISSN - 1052-9276
DOI - 10.1002/1099-1654(200011/12)10:6<385::aid-rmv296>3.0.co;2-1
Subject(s) - antiretroviral therapy , context (archaeology) , medicine , human immunodeficiency virus (hiv) , intensive care medicine , antiretroviral agents , immunology , virology , viral load , biology , paleontology
The availability of potent combination antiretroviral therapy (ART), also known as highly active antiretroviral therapy or HAART has changed the prognosis of HIV infection. However, the benefits have to be seen in the context of deficiencies of current therapy: failure to eradicate the virus, the slow and potentially incomplete recovery of the immune system, the high prevalence of resistance, and the potential for long‐term toxicity. Treatment strategies need to take into account these limits to better target those HIV‐infected patients who could benefit the most from antiretroviral therapy. Copyright © 2000 John Wiley & Sons, Ltd.