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Inhibition of Lipogenesis by pycnogenol
Author(s) -
Hasegawa Noboru
Publication year - 2000
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/1099-1573(200009)14:6<472::aid-ptr649>3.0.co;2-s
Subject(s) - lipogenesis , adipose tissue , endocrinology , medicine , chemistry , lipid metabolism , insulin , dehydrogenase , biochemistry , pharmacology , enzyme
The influence of pycnogenol on the adipose conversion of 3T3‐L1 cells by insulin was studied. In week 3 of culture with insulin, pycnogenol was found to inhibit significantly the expression of glycerophosphate dehydrogenase ( p < 0.01). This finding suggests that pycnogenol inhibits the accumulation of lipid droplets in adipose tissue. Copyright © 2000 John Wiley & Sons, Ltd.