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The ameliorating effects of the cognitive‐enhancing Chinese herbs on scopolamine‐induced amnesia in rats
Author(s) -
Hsieh MingTsuen,
Peng WenHuang,
Wu ChiRei,
Wang WenHsin
Publication year - 2000
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/1099-1573(200008)14:5<375::aid-ptr593>3.0.co;2-5
Subject(s) - panax notoginseng , traditional medicine , polygonum , cyperus rotundus , salvia miltiorrhiza , angelica sinensis , gastrodia elata , ginseng , amnesia , nootropic , scutellaria baicalensis , rehmannia glutinosa , pharmacology , medicine , traditional chinese medicine , alternative medicine , pathology , psychiatry
Ameliorating effects were investigated of the cognitive‐enhancing Chinese herbs administered orally for 1 week— Panax ginseng (PG), Panax notoginseng (PNG), Dioscorea opposita (DO), Gastrodia elata (GE), Salvia miltiorrhiza (SM), Acorus gramineus (AG), Coptis chinensis (CC), Polygonum multiflorum (PM), Cyperus rotundus (CR) and Psoralea corylifolia (PC)—on the scopolamine (SCOP)‐induced amnesia by using a passive avoidance task in rats. Of ten Chinese herbs, only PG, PNG, GE and CC prolonged the SCOP‐shortened STL. These results revealed that PG, PNG GE and CC administered orally for 1 week improved the SCOP‐induced learning and memory deficit in rats. Copyright © 2000 John Wiley & Sons, Ltd.