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Acute and subacute toxicity of Cochlospermum regium (Mart. & Schr.) Pilger
Author(s) -
Toledo Maria I.,
Siqueira João M.,
Araújo Luciane C. L.,
Oga S.
Publication year - 2000
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/1099-1573(200008)14:5<359::aid-ptr642>3.0.co;2-0
Subject(s) - toxicity , acute toxicity , traditional medicine , pharmacology , medicine , oral administration , pharmacognosy , biology , biological activity , in vitro , biochemistry
The toxicity of a hydroethanol extract of the subterranean part of Cochlospermum regium was evaluated in mice and rats. The extract had moderate acute toxicity when administered intraperitoneally and low toxicity upon oral administration. A subacute toxicity test revealed that the extract is well tolerated by these animals. Copyright © 2000 John Wiley & Sons, Ltd.