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Separation and NMR studies on lignans of Raulinoa echinata
Author(s) -
Biavatti Maique W.,
Vieira Paulo C.,
da Silva M. Fátima G. F.,
Fernandes João B.,
Degani Ana L. G.,
Cass Quezia B.,
Schefer Alexandre B.,
Ferreira Antônio G.
Publication year - 2001
Publication title -
phytochemical analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 72
eISSN - 1099-1565
pISSN - 0958-0344
DOI - 10.1002/1099-1565(200101/02)12:1<64::aid-pca562>3.0.co;2-3
Subject(s) - chemistry , lignan , chromatography , organic chemistry
Investigation of the leaves of Raulinoa echinata Cowan (Rutaceae) has led to the isolation of several furofuran (2,6‐diaryl‐3,7‐dioxabicyclo[3.3.0]‐octane) lignan derivatives, namely (+)‐sesamin, (+)‐eudesmin, (+)‐methylpiperitol (= kobusin), (+)‐piperitol‐γ,γ‐dimethylallylether and the corresponding epi compounds: (+)‐asarinin, (+)‐epieudesmin, (+)‐methylxanthoxylol, (+)‐methylpluviatilol, (+)‐xanthoxylol‐γ,γ‐dimethylallylether and (+)‐pluviatilol‐γ,γ‐dimethylallylether. This is the first report of the chromatographic separation of the epimers (+)‐methylxanthoxylol/(+)‐methylpluviatilol and (+)‐xanthoxylol‐γ,γ‐dimethylallylether/(+)‐pluviatilol‐γ,γ‐dimethylallylether and of their NMR nOe difference studies. Copyright © 2001 John Wiley & Sons, Ltd.