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A study of the cyclodextrin complexes of flavonoids and azodyes by thin layer chromatography. Part II. Hydroxypropyl‐cyclodextrins
Author(s) -
Hostettmann K.,
Lederer M.,
Marston A.
Publication year - 2000
Publication title -
phytochemical analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 72
eISSN - 1099-1565
pISSN - 0958-0344
DOI - 10.1002/1099-1565(200011/12)11:6<380::aid-pca530>3.0.co;2-4
Subject(s) - chemistry , elution , cyclodextrin , chromatography , solubility , aqueous solution , adsorption , thin layer chromatography , cellulose , organic chemistry
2‐Hydroxypropyl‐β‐cyclodextrin (1) was recently advocated for general solubility enhancement in pharmacy. In view of this, data are presented of the behaviour of flavonoids, azodyes and other compounds in adsorption chromatography on cellulose layers eluted with aqueous solvents containing various concentrations of 1. The results show that elution is not very different from that previously observed with β‐cyclodextrin except that complete elution of many compounds can be obtained with high concentrations (10–20%) of 1. Copyright © 2000 John Wiley & Sons, Ltd.