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Flip angle considerations in 3 Helium‐MRI
Author(s) -
Markstaller Klaus,
Eberle Balthasar,
Schreiber Wolfgang G.,
Weiler Norbert,
Thelen Manfred,
Kauczor HansUlrich
Publication year - 2000
Publication title -
nmr in biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 114
eISSN - 1099-1492
pISSN - 0952-3480
DOI - 10.1002/1099-1492(200006)13:4<190::aid-nbm644>3.0.co;2-m
Subject(s) - flip angle , nuclear magnetic resonance , lung ventilation , signal (programming language) , helium , lung function , magnetic resonance imaging , diffusion mri , physics , materials science , nuclear medicine , computer science , lung , medicine , radiology , atomic physics , programming language
3 Helium‐MRI ( 3 He‐MRI) can be used for analysis of lung function, e.g. dynamic imaging of ventilation and gas diffusion within the lung, assessment of intrapulmonary oxygen concentrations and their time course. During imaging, the irreversible signal loss due to depolarizing radio frequency excitations can be described using the flip angle (FA) α. This parameter has to be quantified in order to account for it during quantitative assessment of the 3 helium signal intensity and its temporal development. This technical report reviews two different methods to determine α. Limitations and possible error sources of each method are discussed. Copyright © 2000 John Wiley & Sons, Ltd.