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A cinchonidine derivative for photoaffinity labelling of proteins
Author(s) -
Deady Leslie W.,
Desneves Jose,
Tilley Leann M.
Publication year - 2000
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/1099-1344(200009)43:10<977::aid-jlcr382>3.0.co;2-e
Subject(s) - chemistry , labelling , cinchonidine , amide , derivative (finance) , photoaffinity labeling , affinity label , combinatorial chemistry , stereochemistry , organic chemistry , biochemistry , binding site , enantioselective synthesis , enzyme , catalysis , financial economics , economics
8‐Aminohydrocinchonidine was prepared and coupled with 4‐azidosalicyclic acid. The resulting amide was labelled with 125 I to produce a photoactivatable species for attaching to proteins. Copyright © 2000 John Wiley & Sons, Ltd.