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Evidence‐based medicine and health economics: a case study of end stage renal disease
Author(s) -
Vale Luke,
Donaldson Cam,
Daly Conal,
Campbell Marion,
Cody June,
Grant Adrian,
Khan Izhar,
Lawrence Paul,
Wallace Shiela,
Macleod Alison
Publication year - 2000
Publication title -
health economics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.55
H-Index - 109
eISSN - 1099-1050
pISSN - 1057-9230
DOI - 10.1002/1099-1050(200006)9:4<337::aid-hec518>3.0.co;2-o
Subject(s) - observational study , randomized controlled trial , economic evaluation , systematic review , end stage renal disease , medicine , intensive care medicine , health economics , cost effectiveness , medline , management science , disease , risk analysis (engineering) , economics , surgery , public health , nursing , pathology , political science , law
This paper explores the potential for use of an economic evaluation framework alongside systematic reviews. Clinical issues in dialysis therapy for end stage renal disease are used as case studies. The effectiveness data required were obtained from a systematic review of randomized controlled trials. Resource use and cost data were obtained from three sources; the identified randomized controlled trials, a separate review of observational studies and primary data collection. The results of the case studies show that, although simple economic evaluations were possible, issues arose, such as how transferable results are between settings and how appropriate it is to focus on the average patient. The interface between economic evaluation and systematic reviews needs to be further developed in order to ensure that the best available evidence can be used to inform future policy and research. Copyright © 2000 John Wiley & Sons, Ltd.