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Hyphenated chromatographic methods for biomaterials
Author(s) -
AlDirbashi Osama Y.,
Nakashima Kenichiro
Publication year - 2000
Publication title -
biomedical chromatography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 65
eISSN - 1099-0801
pISSN - 0269-3879
DOI - 10.1002/1099-0801(200010)14:6<406::aid-bmc31>3.0.co;2-v
Subject(s) - chemistry , capillary electrophoresis , chromatography , mass spectrometry , atmospheric pressure chemical ionization , detection limit , analytical chemistry (journal) , gas chromatography , chemical ionization , ionization , ion , organic chemistry
The improvement in hyphenated analytical techniques has significantly widened their applications to the analysis of biomaterials. In this article, we discuss recent advances in applications of hyphenated chromatographic techniques including capillary electrophoresis to the analyses of biological samples. As tools of separation, gas chromatography, high‐performance liquid chromatography and capillary electrophoresis are considered with special emphasis on applications utilizing the hyphenation of these methods to mass spectrometry. Moreover, applications using other detection methods such as Fourier transform infrared spectroscopy hyphenated to gas chromatography and photodiode array detector combined with high‐performance liquid chromatography or capillary electrophoresis are also discussed. Owing to their high sensitivity, luminescence‐based detection systems such as laser‐induced fluorescence and chemiluminescence are also included in this review. Copyright © 2000 John Wiley & Sons, Ltd. Abbreviations used: 4‐ABP 4‐aminobiphenylAPCI atmospheric pressure CIAPI atmospheric pressure ionizationBPDEI (+)‐ anti ‐benzo[ a ]pyrene‐diol‐epoxideCE capillary electrophoresisCI chemical ionizationDAD photodiode array detectorEI electron impactFTIR Fourier transform infraredHDA 1,6‐hexamethylene diamineICP‐MS inductively coupled plasma‐MSLIF laser‐induced fluorescenceLOD limit of detectionMP methamphetamineMRM multiple reaction monitoring4‐NPs 4‐nonylphenolsPCBs polychlorinated biphenylsSIM single ion monitoringTSP thermospray.