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Comparison of the tandem mass spectrometry analysis of compounds of general structure R 2 R′SnPh, RR′SnPh 2 with R 4 Sn analogues
Author(s) -
Lawson G.,
Ostah N.
Publication year - 2000
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/1099-0739(200012)14:12<874::aid-aoc110>3.0.co;2-l
Subject(s) - chemistry , fragmentation (computing) , mass spectrometry , aryl , mass spectrum , tandem mass spectrometry , alkyl , medicinal chemistry , electron ionization , tandem , ion , stereochemistry , organic chemistry , chromatography , materials science , composite material , computer science , ionization , operating system
Positive ion‐electron impact (EI) mass spectra of some novel organotin compounds have been recorded. These compounds were of the type Me 2 SnRR′ (where R = Me, Ph and R′ = Ph) and R 2 R′SnPh (where R = Me, n ‐Bu, n ‐Pe and R′ = Me, n ‐Bu, n ‐Pe). The spectra were also examined by tandem mass spectrometry (MS–MS) in order to establish fragmentation reaction mechanisms for compounds bearing mixed substituents, particularly the effect of the presence of aryl substituents. In addition, the resultant EI and MS–MS spectra for these compounds were compared with those of R 4 Sn (R = Me, Bu, Pe, Ph). The results show that mixed substitution of tetra‐alkyl/aryl compounds has a significant effect on the behaviour of these compounds in the mass spectrometer. This effect can be illustrated by examining the fragmentation reaction pathways for the various compounds studied. Fragmentation patterns of nine organotin compounds, based on precursor–product ion relationships are proposed. This technique has the potential to predict the effect of substitution on the mass spectra of organotin compounds and probably organolead and organogermanium compounds. Copyright © 2000 John Wiley & Sons, Ltd.