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Triphenyltin(IV) sulfanylpropenoates: synthesis, crystal structures and antimicrobial activities
Author(s) -
Casas J. S.,
Castiñeiras A.,
Couce M. D.,
Jorge M. L.,
Russo U.,
Sánchez A.,
Seoane R.,
Sordo J.,
Varela J. M.
Publication year - 2000
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/1099-0739(200008)14:8<421::aid-aoc18>3.0.co;2-8
Subject(s) - chemistry , isopropylamine , ligand (biochemistry) , crystal structure , medicinal chemistry , nuclear magnetic resonance spectroscopy , stereochemistry , antimicrobial , nuclear chemistry , organic chemistry , biochemistry , receptor
Three new triphenyltin(IV) sulfanylcarboxylates with the general formula [Q][SnPh 3 (L)] (Q = di‐isopropylammonium cation; L = tspa, pspa or pyspa, where t = 3‐(2‐thienyl)‐, p = 3‐(2‐phenyl)‐, py = 3‐(2‐pyridinyl)‐ and spa = 2‐sulfanylpropenoato) have been prepared by reaction of triphenyltin(IV) hydroxide with the corresponding acid in the presence of di‐isopropylamine in ethanol. The compounds have been characterized by elemental analysis and mass spectrometry and by IR, Mössbauer and NMR ( 1 H, 13 C, 119 Sn) spectroscopy. X‐ray studies of the crystal structures of [Q][SnPh 3 (pspa)] and [Q][SnPh 3 (pyspa)] show that in both compounds the tin atom is coordinated to three phenyl C atoms and to S and one O atom of the ligand L. All three complexes are active against strains of the Gram‐positive bacterium Staphylococcus aureus , but are inactive or only slightly active against the Gram‐negative bacteria Escherichia coli and Pseudomonas aeruginosa . Copyright © 2000 John Wiley & Sons, Ltd.