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Dimeric Stilbene Glycosides from Polygonum cuspidatum
Author(s) -
Xiao Kai,
Xuan Lijiang,
Xu Yaming,
Bai Donglu,
Zhong Dexin,
Wu Houming,
Wang Zhonghua,
Zhang Naixia
Publication year - 2002
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/1099-0690(20022)2002:3<564::aid-ejoc564>3.0.co;2-f
Subject(s) - chemistry , glycoside , stereochemistry , cleavage (geology) , two dimensional nuclear magnetic resonance spectroscopy , biochemistry , geotechnical engineering , fracture (geology) , engineering
Two dimeric stilbene glycosides were isolated from an aqueous extract of the root of Polygonum cuspidatum . Their structures were established based on chemical evidence and spectroscopic techniques, including extensive 2D NMR methods. One of these glycosides possesses a novel four‐membered ring. Both compounds exhibit strong inhibition of lipid peroxidation, but show no cytotoxic, DNA‐cleavage activities and no inhibition of protein tyrosine phosphatase 1B (PTP1B).