Premium
On the Tautomerism of 2,4‐Disubstituted Thiazolones
Author(s) -
Lin Yuhui,
Andersen Kenneth K.
Publication year - 2002
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/1099-0690(20022)2002:3<557::aid-ejoc557>3.0.co;2-7
Subject(s) - tautomer , chemistry , alkoxy group , computational chemistry , stereochemistry , medicinal chemistry , organic chemistry , alkyl
Four series of thiazolones − 2‐phenyl‐, 2‐ethyl, 2‐ethoxy, and 2‐(ethylthio)thiazol‐5‐ones − have been synthesized. The tautomeric behavior of these thiazolones is discussed, and the keto form II, i.e. 2‐ethylthiazol‐5(2 H )one has been characterized by IR, 1 H and 13 C NMR spectroscopic methods for the first time.