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New Strategies for the Synthesis of Carbocycles Based on Transition Metal Catalyzed Cyclization Reactions of Organostannanes and Organosilanes
Author(s) -
Méndez María,
Echavarren Antonio M.
Publication year - 2002
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/1099-0690(20021)2002:1<15::aid-ejoc15>3.0.co;2-0
Subject(s) - chemistry , electrophile , nucleophile , intramolecular force , alkyne , palladium , catalysis , transition metal , organic chemistry , diene , medicinal chemistry , natural rubber
Intramolecular reactions between organosilanes or organostannanes and (η 3 ‐allyl)palladium complexes give rise to a variety of functionalized carbocycles. Conceptually related cyclizations catalyzed by Pd II (or a related electrophilic metal) proceed by coordination of a 1,3‐diene or alkyne with the electrophilic metal, followed by nucleophilic attack by the allylsilane or allylstannane.