Premium
Iodide‐Catalysed Cyclization of Unsaturated N ‐Chloroamines: A New Way to Synthesise 3‐Chloropiperidines
Author(s) -
Noack Michael,
Göttlich Richard
Publication year - 2002
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/1099-0690(200209)2002:18<3171::aid-ejoc3171>3.0.co;2-l
Subject(s) - chemistry , iodide , catalysis , organic chemistry , medicinal chemistry
Tetrabutylammonium iodide is a very efficient catalyst for the cyclization of unsaturated N ‐chloroamines. The catalysis seems to proceed through N ‐iodoamine intermediates, which act as a source of iodonium ions. (© Wiley‐VCH Verlag GmbH, 69451 Weinheim, Germany, 2002)