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A Valuable Approach to Enantiopure Partially Saturated Pyrrolo‐ and Indolo[1,2‐ a ]indoles by Intramolecular Nitrone Cycloadditions to the Cyclohexene Ring
Author(s) -
Beccalli Egle M.,
Broggini Gianluigi,
Farina Alessandra,
Malpezzi Luciana,
Terraneo Alberto,
Zecchi Gaetano
Publication year - 2002
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/1099-0690(200207)2002:13<2080::aid-ejoc2080>3.0.co;2-3
Subject(s) - enantiopure drug , chemistry , nitrone , intramolecular force , ring (chemistry) , pyrrole , indole test , stereochemistry , cycloaddition , organic chemistry , enantioselective synthesis , catalysis
Enantiopure representatives of the title heterocyclic systems, which are of interest in alkaloid chemistry, are accessible by a procedure based upon intramolecular cycloadditions of nitrones derived from N ‐(cyclohex‐2‐enyl)‐substituted pyrrole‐2‐ and indole‐2‐carbaldehyde, followed by reductive manipulation of the cycloadducts. (© Wiley‐VCH Verlag GmbH, 69451 Weinheim, Germany, 2002)