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Bi 0 ‐Catalyzed Oxidation of Mandelic Acid Derivatives: Substrate Selectivity
Author(s) -
Favier Isabel,
Giulieri Françoise,
Duñach Elisabet,
Hébrault Dominique,
Desmurs JeanRoger
Publication year - 2002
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/1099-0690(200206)2002:12<1984::aid-ejoc1984>3.0.co;2-3
Subject(s) - chemistry , mandelic acid , selectivity , benzaldehyde , benzoic acid , catalysis , substrate (aquarium) , bismuth , organic chemistry , ring (chemistry) , combinatorial chemistry , medicinal chemistry , oceanography , geology
A series of mandelic acid derivatives was oxidized with a bismuth‐catalyzed oxidation system based on Bi 0 /DMSO/O 2 . Benzaldehyde and/or benzoic acid derivatives could be obtained chemoselectively depending on the catalytic system and the substitution on the aromatic ring. A strong substrate selectivity was observed, suggesting different oxidation mechanisms. (© Wiley‐VCH Verlag GmbH, 69451 Weinheim, Germany, 2002)