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Synthesis of Furo[3,2‐ g ][1,4]Benzoxazin‐3‐ones, New Psoralen Isosters
Author(s) -
Chilin Adriana,
Confente Alessia,
Pastorini Giovanni,
Guiotto Adriano
Publication year - 2002
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/1099-0690(200206)2002:12<1937::aid-ejoc1937>3.0.co;2-w
Subject(s) - chemistry , psoralen , coumarin , ring (chemistry) , benzofuran , furan , tricyclic , stereochemistry , nucleus , organic chemistry , dna , biochemistry , biology , microbiology and biotechnology
Furobenzoxazin‐3‐one, a new tricyclic nucleus, was synthesised in two different and straightforward routes: the first route consisted of condensing a furan ring onto a preconstituted 1,4‐benzoxazinone nucleus, and the other in condensing a 1,4‐oxazine ring onto the appropriate benzofuran system obtained from coumarin by ring contraction. (© Wiley‐VCH Verlag GmbH, 69451 Weinheim, Germany, 2002)