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The Synthesis of Solvent‐Free Glycidic Esters from Diazoesters and Carbonyl Compounds Catalysed by Lanthanide Triflates
Author(s) -
Curini Massimo,
Epifano Francesco,
Marcotullio Maria Carla,
Rosati Ornelio
Publication year - 2002
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/1099-0690(200205)2002:9<1562::aid-ejoc1562>3.0.co;2-q
Subject(s) - chemistry , lanthanide , organic chemistry , solvent , catalysis , ethyl diazoacetate , medicinal chemistry , ion , cyclopropanation
The results of the reaction between ethyl diazoacetate and carbonyl compounds catalysed by lanthanide triflates are described. Aldehydes, and α‐unsubstituted and α‐monosubstituted cyclohexanones react to give the selective formation of α,β‐epoxy esters (glycidic esters), whereas other ketones are unreactive. (© Wiley‐VCH Verlag GmbH, 69451 Weinheim, Germany, 2002)